![]() 4 Untreated poststroke OSA is associated with increased risk of recurrent stroke and death, 5 prolonged hospital admissions, 6 and poorer functional outcome. OSA is detected in about 70% of stroke/transient ischemic attack (TIA) survivors 3 and remains prevalent even 3 years after stroke. ![]() 2 Multiple mechanisms may contribute to the risk of cardiovascular disease such as sympathetic activation, impaired endothelial function, hypercoagulability, inflammation, and oxidative stress. Obstructive sleep apnea (OSA) is a common disorder characterized by recurrent partial or complete collapse of the upper airway during sleep, 1 which exposes the cardiovascular system to physiological stressors such as nocturnal oxygen desaturation, arousals from sleep, and intrathoracic pressure changes.
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